Esketamine (Spravato)
Registered 2021 — valid to 2029Spravato received a registro sanitario M-US-19-00469 in 2021 (per Janssen statements; valid until 05 June 2029). Esketamine is a named national controlled psychotropic.
Last updated 18 August 2026
Psychedelic Therapy Legal Landscape
Spravato received a registro sanitario M-US-19-00469 in 2021 (per Janssen statements; valid until 05 June 2029). Esketamine is a named national controlled psychotropic.
Ketamine is a named national controlled psychotropic, legal as a hospital anesthetic under the receta verde regime (CCSS confirms supervised in-patient use). Sparsely documented — treat any private offer with standard scrutiny.
Psilocybin retreats operate in a legal gray zone; no medical framework exists. Psilocybin is technically on the controlled list, and Law 8204 sets no quantity threshold — but Costa Rican courts require proof of trafficking intent to convict, so bare personal possession/consumption is in practice not prosecuted. That’s not the same as legal supply.
No medical framework.
The drug law does not penalize personal consumption (no defined threshold — de facto decriminalization); an adult-use bill proposed in 2022 never passed. No legal supply.
Ibogaine is not on the national schedule — health officials call it simply “unregistered,” not authorized for therapeutic use — but the health ministry’s 23 January 2025 warning covers it explicitly alongside ayahuasca (which is scheduled, via its DMT content). Given ibogaine’s cardiac risk, an unregulated setting is exactly where it is most dangerous.
No significant registered psychedelic trial activity. Participation is free; screening is strict; never pay for “trial access”.