5-MeO-DMT for Mental Health and Transformation
15 minutes is enough to dissolve the self completely. What 5-MeO-DMT does to the brain, what the clinical trials show, and where the risks sit.
Your Psychedelic Hub:
Learn The Way You Like
Substance guides, therapy guides, self-checks, tools for preparation and integration, and safety resources: all in one place to help you prepare, navigate, and stay informed all the way through.
Substance guides
Comprehensive breakdowns of psychedelics, dissociatives, and plant-based medicines — what they do, risks, and access
Ayahuasca for Mental Health and Personal Growth
Explore ayahuasca’s effects, benefits, and risks, including its potential impact on depression, anxiety, personal growth, and current mental health research.
Psychedelics for Longevity: Can They Support Healthy Aging?
Explore how psychedelics may support healthy aging through brain health, stress resilience, and neuroplasticity, backed by current research.
Therapy guides
PAT fundamentals, clinic navigation, integration resources, and safety-first harm reduction — your complete reference
How to Choose a Psychedelic Therapy Provider
Psychedelic-assisted therapy requires thorough due diligence. With this guide, find the right psychedelic provider, including what credentials to look for, questions to ask, and red flags — with…
How to Choose a Psychedelic Therapy Clinic Offering Guided Sessions
Navigate providers offering guided sessions — with insights from Clínica Synaptica in Barcelona.
Microdosing FAQ: Theory Meets Practice
Does microdosing actually improve sleep, focus or creativity? 3 practitioners answer the most-asked questions: benefits, side effects, psilocybin vs LSD — and when not to microdose.
The most important conversations shaping the future of psychedelics, delivered weekly.
From thought-provoking podcasts and original stories to research breakthroughs and industry news, stay connected to the conversations that matter.
Joined by 12,000+ readers
Self-checks
Evidence-based self-checks for psychedelic therapy eligibility and mental health conditions — all under 7 minutes
Tools & Practices
Collection of preparation guides, integration workbooks, harm reduction tools, and support resources
Preparation
Substance guides • Prep workbook • Set & Setting • Readiness quiz
Session Day
Day-of checklist • Playlists • Educational videos
Integration
Workbook • 30-day email program • Meditation library • Journal
Harm Reduction
Safety guide • Difficult experiences • Trip-sitter guide
Preparation
4 substances
Each psychedelic substance has a unique pharmacological profile, duration, and experiential character. Understanding what to expect — including timeline, physical sensations, and common challenges — helps you meet the experience with openness rather than fear.
Onset
20–60 minutes
Peak
2–4 hours
Total Duration
4–6 hours
After-effects
Up to 24 hours
Onset
30–90 minutes
Peak
3–5 hours
Total Duration
8–12 hours
After-effects
Up to 48 hours
Onset
30–60 minutes
Peak
1.5–3 hours
Total Duration
4–6 hours
After-effects
24–72 hours
Onset
1 to 15 minutes
Peak
30–60 minutes
Total Duration
1–2 hours
After-effects
Hours
Checklists: What’s Inside?
Practical support from start to finish: intention-setting, session preparation, integration work, and emergency support.
- Psychedelic Preparation Workbook
- Set & Setting Checklist
- Session-Day Checklist
- Integration Exercises
- Difficult Moments Cards
For researchers, journalists, and curious minds
Psychedelic Research Tool
Explore psychedelic studies, insights, and findings in one searchable place.
Coming soon
For first-timers and intentional explorers
Preparation Assistant
A chat-based guide to help you prepare for a psychedelic experience with more clarity, intention, and safety.
Coming soon
For post-experience reflection and integration
Integration Assistant
A guided tool to help users reflect on their experience, capture insights, and turn them into meaningful next steps.
