Esketamine (Spravato)
HSE-reimbursedHSE-reimbursed since January 2022 for treatment-resistant depression — psychiatrist-initiated, in combination with an SSRI/SNRI, delivered through a limited number of specialist psychiatric services.
Ireland
Last updated 18 August 2026
Psychedelic Therapy Legal Landscape
Ketamine Therapy
Announced, not yet runningThe private route is thin: Neuromed Clinic (Dublin/Galway) has announced a KAP programme launching autumn 2026, prices unpublished.
Psilocybin
Trials only — CYB003 recruitingResearch-only, but the scene is real: the CYB003 Phase 3 (EMBRACE) is recruiting in Dublin (Tallaght) and Galway, and the Trinity/Tallaght group ran Ireland’s part of the landmark COMP360 trial.
MDMA
Not available — never trialledNo Irish MDMA trial has ever recruited, and none is open as of July 2026.
Medical Cannabis
Legal but very narrow (MCAP)The Medical Cannabis Access Programme (regulations 2019, operational 2021) covers just three conditions — and only 74 patients were approved in its first five years; a formal review began in April 2026. A parallel Ministerial Licence route exists. Recreational: illegal; the 2024 Citizens’ Assembly recommended decriminalization, not enacted.
Clinical Trials
Open route13 studies tracked, 2 active — Trinity College Dublin / Tallaght anchor the scene. Recruiting: Cybin CYB003 Phase 3 (Dublin, Galway). Participation is free; screening is strict; never pay for “trial access”.
Frequently asked questions — Ireland
Is ketamine therapy legal in Ireland?
Announced, not yet running. The private route is thin: Neuromed Clinic (Dublin/Galway) has announced a KAP programme launching autumn 2026, prices unpublished.
Is psilocybin legal in Ireland?
Trials only — CYB003 recruiting. Research-only, but the scene is real: the CYB003 Phase 3 (EMBRACE) is recruiting in Dublin (Tallaght) and Galway, and the Trinity/Tallaght group ran Ireland's part of the landmark COMP360 trial.
Is MDMA therapy legal in Ireland?
Not available — never trialled. No Irish MDMA trial has ever recruited, and none is open as of July 2026.
Can I join a psychedelic clinical trial in Ireland?
13 studies tracked, 2 active — Trinity College Dublin / Tallaght anchor the scene. Recruiting: Cybin CYB003 Phase 3 (Dublin, Galway). Participation is free; screening is strict; never pay for "trial access".
