Condition

Psychedelics for ADHD: what the evidence shows

Long-standing problems with attention, restlessness and impulsivity, here in adults.

Last reviewed 23 October 2026Re-checked every month2 substances with published evidence

Where are these treatments legal?See country-by-country rules on our Psychedelic Therapy Legality Map

Substance by substance

One card per substance, strongest evidence first. A substance that isn’t here has no published clinical evidence for this condition yet.

Medical cannabis

Early research

One small trial missed its main goal.

In a 30-person randomised trial, a THC/CBD spray (Sativex) didn't significantly improve the main measure of attention and activity.¹

Everything medical cannabis has been tested for →

LSD

Little or no evidence

Properly tested — and microdosing didn't work.

In a placebo-controlled trial of 53 adults, LSD microdoses twice a week for six weeks did no better than placebo. Both groups improved, and those who believed they got LSD improved more.²

Everything LSD has been tested for →

Keep reading

Mushrooms for ADHD: Can Microdosing Psilocybin Relieve Symptoms?Psilocybin hasn’t been shown to treat ADHD. What people who microdose report, and why it differs.Read the article

The Rise of ADHD: Awareness or Overdiagnosis?Are adults being overdiagnosed, or is ADHD finally getting the attention it deserves?Read the article

Can Lion’s Mane Help With ADHD?What the research says about lion's mane mushroom for focus and ADHD, and how far the evidence goes.Read the article Research databaseNew studies, summarisedHundreds of papers on psychedelics and mental health, each with a plain-language summary and key facts.Browse the database

Sources

Numbered in the order they appear above. We only use peer-reviewed papers, official company announcements (for trial status and topline results), regulators and trial registries.