2025
4 citations Research paper

Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review

Shakila Meshkat, Gunjan Malik, Richard J. Zeifman, Jennifer Swainson, Krishna Balachandra, Amy C. Reichelt,

Summary & key facts

This paper is a systematic review that looked at clinical research on using psilocybin (the active ingredient in “magic” mushrooms) to treat substance use disorders, focusing on whether it helps and whether it is safe. The abstract or full text was not provided here, so I cannot report the review’s specific results, numbers, or conclusions. If you share the paper text or abstract, I can summarize the actual findings, what they mean for people, and the study limitations.

Key facts:
  • The paper is a systematic review, which means the authors collected and evaluated multiple studies on the same question: whether psilocybin helps treat substance use problems and whether it is safe.
  • Psilocybin is the psychedelic compound found in certain mushrooms and is being studied as a possible treatment for mental health and addiction problems.
  • A systematic review typically looks at study methods, results, and safety reports to judge how strong and consistent the evidence is across studies.
  • Because the abstract or main text was not included here, I cannot say what the review actually found about benefits, risks, or how many people or studies were included.
  • If you provide the paper’s abstract or a link to the full text, I can describe the review’s actual results, how strong the evidence seems, and any important limitations the authors noted.

Topics

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Categories

Clinical Psychology Psychology Social Sciences

Tags

Hallucinogen Medicine Psilocybin Psychiatry Psychology Psychotherapist Substance use

Substances

Psilocybin

Conditions & symptoms

Addiction Substance abuse disorder Addiction or harmful habbits
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.

Referencing articles

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Expert-Reviewed by: Dr. Grischa Judanin