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2025
12 citations Research paper

Efficacy and safety of psilocybin for the treatment of substance use disorders: A systematic review

Shakila Meshkat, Gunjan Malik, Richard J. Zeifman, Jennifer Swainson, Krishna Balachandra, Amy C. Reichelt,

Summary & key facts

This paper is a systematic review that looked at research on using psilocybin (the active compound in 'magic mushrooms') to treat people with substance use disorders, and at whether it is safe to use for that purpose. The short excerpt provided here does not include the review's results or numbers, so I cannot say what the authors concluded about how well psilocybin works or how risky it is. If you want to know the actual outcomes, you would need to read the full paper for the review's findings, the kinds of studies it included, and the authors' notes about limits and safety.

Key facts:
  • The paper is a systematic review, which means the authors searched for and summarized existing studies about psilocybin for substance use problems.
  • The review focused on two main questions: whether psilocybin helps treat substance use disorders, and whether it is safe for people in that context.
  • The excerpt provided here does not contain the review's results, so this summary does not report any specific effectiveness or safety findings from the paper.
  • A systematic review does not run new drug tests on people; it examines and combines results from earlier studies to give an overall picture of the evidence.
  • To know what the review actually found — for example, whether psilocybin reduced use of alcohol or other drugs, or what side effects were reported — you need the full article rather than this short excerpt.

Topics

Chemical synthesis and alkaloids Neurotransmitter Receptor Influence on Behavior Psychedelics and Drug Studies

Categories

Clinical Psychology Psychology Social Sciences

Tags

Hallucinogen Medicine Psilocybin Psychiatry Psychology Psychotherapist Substance use

Substances

Psilocybin

Conditions & symptoms

Addiction Substance abuse disorder Addiction or harmful habbits
Summaries and links are for general information and education only. They are not a substitute for reading the original publication or for professional medical, legal, or other advice. Always refer to the linked source for the full study.

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