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2025 0 citations Research paper

Cognitive and subjective effects of psilocybin microdosing: Results from two double-blind placebo-controlled longitudinal trials

Luisa Prochazkova, Josephine Marschall, Dominique P. Lippelt, Neil R Schon, Martin Kuchař, Bernhard Hommel

Summary & key facts

This paper reports two carefully controlled trials that tested very low “micro” doses of psilocybin against a placebo and followed participants over time. The studies looked at both thinking skills (cognitive effects) and how people felt (subjective effects). I don’t have the paper’s abstract text here, so I can’t say exactly what the trials found or what that means for people. Please paste the abstract or key results and I’ll give a clear, plain-language summary of the findings and their real-life meaning.

Key facts:
  • The paper describes two double-blind, placebo-controlled longitudinal trials — meaning people were randomly given either microdoses or fake pills and both participants and researchers didn’t know who got which, and they were followed over time.
  • The focus was on psilocybin microdosing — very low doses of the psychedelic substance psilocybin — and on measuring both cognitive performance (thinking skills) and subjective reports (how people said they felt).
  • The study is published in the journal Neuropharmacology in 2025 under the title ‘Cognitive and subjective effects of psilocybin microdosing: Results from two double-blind placebo-controlled longitudinal trials’.
  • I don’t have the abstract or result details in the message you gave me. I need the paper’s abstract or key result text to summarize the actual findings and what they mean for people.

Topics

Psychedelics and Drug Studies

Categories

Clinical Psychology Psychology Social Sciences

Tags

Clinical psychology Clinical trial Cognition Cognitive Assessment System Cognitive psychology Developmental psychology Hallucinogen Longitudinal study Psilocybin Psychology Psychotherapist

Substances

Psilocybin
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