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Condition

Psychedelics for insomnia & sleep: what the evidence shows

Trouble falling or staying asleep, or sleep that doesn't feel restful.

Last reviewed 23 October 2026Re-checked every month1 substances with published evidence

Where are these treatments legal?See country-by-country rules on our Psychedelic Therapy Legality Map

Substance by substance

One card per substance, strongest evidence first. A substance that isn’t here has no published clinical evidence for this condition yet.

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Sources

Numbered in the order they appear above. We only use peer-reviewed papers, official company announcements (for trial status and topline results), regulators and trial registries.

  1. Wang L et al. Medical cannabis or cannabinoids for chronic non-cancer and cancer related pain: a systematic review and meta-analysis of randomised clinical trials. BMJ. 2021Journal